HIBLUP Downloads

HIBLUP is written in C++, the released executable files can be used in terminal of different platform directly, there is no process of installation.
Binary file for different platform can be found below:

Linux

x86_64
v1.2.0
08/19/2022
12.8 MB
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MacOS

x86_64, M1
v1.2.0
08/19/2022
3.2 MB
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Windows

x86_64
v1.2.0
08/19/2022
9.7 MB
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鲲鹏(Kunpeng)

aarch64
v1.1.0
05/24/2022
4.9 MB
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After downloaded successfully, please type ./hiblup --help in the terminal to see all available functions.
The test dataset prepared for running HIBLUP can be downloaded by clicking demo.zip.
For more details, please refer to the Online User Manual.

Update history

Version 1.2.0 19 Aug 2022

  • improve the computational efficiency and lower the memory cost for HE regression.
  • further reduce the memory cost for GRM construction.
  • improve the computational efficiency for PCG algorithm.
  • add a parameter (--he-pred) to control wether to compute the random effects when using HE regression.

Version 1.1.0 15 Apr 2022

  • add the following functions:
    allele frequency (--allele-freq) and genotype frequency (--geno-freq)
    homozygosity (--homo) and heterozygosity (--hete)
    different algorithms for GRM construction (--code-method)
    inbreeding coefficients (--ibc) and relationship coefficients (--rc) from pedigree or genotype
    reliability and PEV for all random effects (--r2)
    PCA (--pca, --npc)
  • fix some bugs and improve the computational efficiency.

Version 1.0.603 26 Nov 2021

  • fixed a bug for constructing GRM.
  • fixed the problem of output alignment of full-width characters.

Version 1.0.592 18 Nov 2021

  • fixed a bug for LU decomposition in variance components estimation.
  • added LU decomposition in MME solver.

Version 1.0.589 21 Oct 2021

  • fixed some bugs proposed by users for a more inclusive experience.

Version 1.0.586 5 Oct 2021

  • release the first version of HIBLUP, including executable file for Linux, User Manual and so on.